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In autoimmune hemolytic anemia, reduced CD47 expression promotes red blood cell destruction, whereas in cancer, elevated CD47 levels enable tumor cells to evade immune surveillance (48)

For example, a mouse model showed a 45% drop in the GSH/GSSG (glutathione disulfide) ratio after just one week of urban air exposure, alongside increased markers of oxidative stress like lipid peroxidation and protein carbonyls

Repeat for the other nostril

In summary, our results suggest that palbociclib induces lipid peroxidation sensitising cells toward ferroptosis, which only occurs when the protection exerted by GPX4 is inhibited

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