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doi: 10.1074/jbc.M113.454538 130 Lussey-LepoutreCHollinsheadKELudwigCMenaraMMorinACastro-VegaLJet al

Animal models of developmental thyroid hormone deficiency have also reproduced marked neurocognitive impairment and growth retardation in offspring, much like in humans with hypothyroidism (Chaulin et al

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TXNRD1 has emerged as a selective vulnerability in KRAS -wild-type and KRAS inhibitor-resistant tumors, where its blockade induces ferroptosis through combined GSH depletion and iron overload 117

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