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The reaction mixture was incubated at 30 C and the consumption of NADH at 10 min was used to derive the reaction rate (velocity) for phosphorylation

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Beta-blockers, especially when delivered as part of guideline-directed medical therapy, decrease the risk of major cardiovascular events, reduce mortality and hospitalization in patients with HFrEF, lessen the symptoms of heart failure, improve the clinical status of these patients, and reduce future clinical deterioration associated with heart failure