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Reported side effects Mild headache or fatigue typically transient during initial use Mild gastrointestinal discomfort reported in some oral formulation users Sleep disruption or irritability potential sign of overstimulation Theoretical safety concerns Critical note: Because Dihexa activates the HGF/c-Met pathway which promotes cellular growth and repair there is a theoretical concern that it could potentially stimulate unwanted cell proliferation in individuals with active cancer or high cancer risk

Bennett, E

Mice were group-housed and maintained at room temperature (2325 C) on a standard chow diet with a 12-h lightdark cycle and free access to water and food unless specified

Cancer metabolism pipeline breaks new ground

A similar pattern of stable increase in levels of GSH and GSSG was observed in Arabidopsis mutant plants with increased resistance ( rbohF ) and HR-like reaction ( rbohD/F ) infected by TuMV (Otulak-Kozie et al., 2023), which was also associated with decreased expression of the virus