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10.1104/pp.010066 32 DesikanR.ReynoldsA.HancockJ

Wisniewski, J

A similar approach was successfully applied to develop selective drug activators of the protein kinase AMPK, which were revealed to bind to an unexpected allosteric site on AMPK that is distinct from the canonical AMP-binding sites [213,214,215,216]

BPC-157 appears to counteract oxidative stress damage through enhancement of antioxidant enzyme systems and reduction of reactive oxygen species in damaged tissues

ER stress is known to be implicated in the pathology of many inflammatory disease models, including LPS-induced lung inflammation (Kim et al., 2013), high-fat diet-induced insulin resistance (Yuzefovych et al., 2013), or chronic graft-versus-host disease (Mukai et al., 2017)