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Clinical Take-Home Messages GLP-1RAs are no longer diabetes-only drugs. They are becoming: Obesity therapies Cardiovascular protective agents Anti-inflammatory therapies Neuroprotective candidates Metabolic disease modifiers Conclusion We are witnessing a historic transition in medicine

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Reported benefits include enhanced glycemic control, weight reduction, and decreased levels of inflammatory markers, suggesting that GLP-1 RAs may modulate immune pathways and proinflammatory cytokine activity involved in the pathogenesis of psoriasis

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Molecules 27(14):4663 Zingale E et al (2022) Drug nanocrystals: focus on brain delivery from therapeutic to diagnostic applications