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Cellular oxidative stress causes the dissociation of the complex, oligomerization of GSTP, and induction of the JNK pathway, resulting in apoptosis

Most commonly via subcutaneous injection near the injury site or systemically

When used in scalp serums, side effects are typically mild and uncommon

Am J Physiol 268:G673G684 Kimura H, Miura S, Shigematsu T, Ohkubo N, Tsuzuki Y, Kurose I, Higuchi H, Akiba Y et al (1997) Increased nitric oxide production and inducible nitric oxide synthase activity in colonic mucosa of patients with active ulcerative colitis and Crohns disease

Vascular injury and thrombotic disorders show interesting preclinical findings with BPC-157 preventing pathological thrombus formation while maintaining physiological hemostasis