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Recent research has highlighted the pivotal involvement of ferroptosis in the pathophysiology of AMD, notably through the Xc and GPX4 pathways, and mitochondrial metabolism (221, 222)

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She explains that these ingredients help address microcirculatory stagnation and oxidative stress, two contributors to undereye swelling. Glycerin and shea butter cushion skin, rice extract smooths, and the cooling metal applicator enhances lymphatic drainage and offers noticeable immediate depuffing, she says