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Melatonin further reinforces insulin sensitivity by synchronizing circadian insulin secretion, improving mitochondrial efficiency in hepatocytes and skeletal muscle, and attenuating the nocturnal cortisol overshoot typical in PCOS (226, 227)

Furthermore, relevant literature has also been reviewed to assist clinicians in the diagnosis of cases characterized by the coexistence of multisystemic symptoms and epileptic manifestations

Probiotic supplementation influences gut microbiome health and may reduce inflammation throughout the digestive tract

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External References National Center for Biotechnology Information (NCBI): Research on Delta Sleep-Inducing Peptide National Institutes of Health (NIH): Information on sleep physiology and sleep regulation July 23-24, 2026: Meeting of the Pharmacy Compounding Advisory Committee