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When the saline-vs-bac-water confusion shows up: Most commonly when a buyer assumes "saline" and "bacteriostatic water" are interchangeable because both are clear, sterile, injectable liquids in similar-looking vials

Before dosing, obtain an estimated creatinine clearance in patients at high risk for renal disease (e.g., older patients, or those with diabetes mellitus, hypertension, or autoimmune disease)

Standard insulin syringes marked in units (100 units = 1 mL) allow accurate measurement of small volumes

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Additional studies will be required to determine whether metformin can increase incretin receptor expression in human beta cells and thereby bolster incretin action in a meaningful way