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A JAMA Internal Medicine study highlighted increased gallbladder disease among semaglutide users, and in 2023, the FDA required label changes to reflect serious gastrointestinal risks

B12 is essential for healthy blood cell production, energy levels, neurotransmitter production, and many other bodily processes

Feldman C, Anderson R

Because the drugs act on powerful metabolic levers, they've also since proven useful against obesity, heart disease, sleep apnea, as well as potentially addiction and now cancer

Patients should be encouraged to adopt sustainable lifestyle changes to support their weight loss treatment goals