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They may be too harsh for the skin

Regarding the positive effect of SGLT2 inhibitors on -cell sensitivity to incretin hormones, the combination of incretin-based therapies and SGLT2 inhibitors could be a very effective option for anti-diabetic treatment

Patrick]: You were, that's right

Clinical evidence consistently shows that patients starting GLP-1 therapy lose weight more rapidly and achieve greater total weight loss than those on metformin alone, even when combining metformin with lifestyle changes

It is important to mention that BAT is a specialized fat depot characterized by increased energy expenditure and heat production (95)