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It follows that drugs used for the treatment of T2D, and especially those that increase bioactivity of gut-derived hormones, could exert added benefits on bone health

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[PMC free article: PMC3326794] [PubMed: 22529679] (Among 92 patients with symptomatic osteoarthritis of the knees treated for 6 weeks with one of four herbal preparations [2 with ashwagandha], adverse events were uncommon and mild, and none of 45 patients developed serum ALT or AST elevations)

At first glance, these two studies might seem contradictory: one suggests that GLP-1 quieted a DMN region, whereas the other reports that GLP-1 increased DMN connectivity

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