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caution in methylation disorders (use only under supervision) No known drug interactions with oral medications, but B12 may mask B9 (folate) deficiencycombined B-vitamin status should be assessed periodically

Obesity is the fastest-growing indication segment, driven by high-efficacy weight loss data, expanded regulatory approvals, and direct-to-consumer demand [1]

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Stefan Cimbollek has received educational sponsorships, speaker fees, and participated in advisory boards and travel grants from Novartis, Pharming, Takeda, CSL Behring, and Biocryst, and participated in clinical trials sponsored by Novartis, Jerini/Shire, CSL Behring, Pharming, and Ionis

Table 2 Original human studies on the physiological determinants of perinatal glucocorticoid sensitivity