Furthermore, hypermethioninemia induces oxidative damage and liver injury (34), hemolytic anemia, and development of its associated symptoms such as jaundice and enlarged liver and spleen in rats (3537)
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While insulin treatment is associated with weight gain, GLP-1 agonists promote weight loss, and may help patients achieve this goal even in combination with insulin (Maiorino 2018)
An adjusted P value cut-off of 0.05 was used and TF candidate expression was visualized using z -score heat maps