The Role of an Empty Stomach Taking these supplements on an empty stomach is generally recommended because it avoids "nutrient competition." When you eat a large meal, your body is busy breaking down proteins, fats, and carbohydrates
Adults who have difficulty absorbing B12 through oral supplements or diet, including those with digestive issues or dietary restrictions
doi: 10.3389/fphar.2026.1736380 Received 10 November 2025 Revised 20 January 2026 Accepted 21 January 2026 Published 10 February 2026 Volume 17 - 2026 Edited by Madhusudan Prasad Singh, All India Institute of Medical Sciences Raipur, India Reviewed by Hemasri Velmurugan, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), India Prachi Arunima, All India Institute of Medical Sciences Raipur, India Updates Copyright 2026 Wali, Rangraze, Khan, Mufti, El-Tanani and Rizzo
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