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That does not mean it has no effect, but it does mean the evidence should be evaluated honestly rather than through clinic marketing

Yao H, Arunachalam G, Hwang JW, Chung S, Sundar IK, Kinnula VL, Crapo JD, Rahman I: Extracellular superoxide dismutase protects against pulmonary emphysema by attenuating oxidative fragmentation of ECM

For instance, LRRK2 gene mutations increase the risk of developing Parkinson's disease with a late onset and less severe phenotype, whereas PARK2 gene mutations are associated with early onset and a more severe phenotype [21]

The key clinical trials discussed here are summarized in Table 2