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While rodent studies have shown C-cell tumour findings with some GLP-1 receptor agonists, the human relevance is unknown, and routine calcitonin monitoring is not recommended in UK practice

Protection of NRK-52E cells, a rat renal proximal tubular cell line, from chemical-induced apoptosis by overexpression of a mitochondrial glutathione transporter

Nat Rev Gastroenterol Hepatol (2022) 19(3):16984

(Sonthalia S, et al

In clinical studies, people reported stronger appetite suppression when injecting in the stomach, but this does not prove that it is a more effective injection site than the others