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Mechanistically, beneficial microbes such as Akkermansia synthesize GABA, which activates the mTOR signaling pathway to promote both M2 macrophage polarization and plasma cell differentiation, sustaining sIgA production and mammary mucosal defense 182

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Glutathione transferase from Trichoderma virens enhances cadmium tolerance without enhancing its accumulation in transgenic Nicotiana tabacum