Fenugreek seeds, when steeped, release soluble fibers that slow carbohydrate absorption
Head-to-head comparison (STEP 8) The STEP 8 trial provides direct side-effect comparison data: 1 Gastrointestinal adverse events: 84.1% with semaglutide vs 82.7% with liraglutide Treatment discontinuation due to adverse events: 13.5% with semaglutide vs 27.6% with liraglutide While the overall rate of gastrointestinal side effects was similar, liraglutide had a substantially higher discontinuation rate
Understanding this distinction helps patients and providers navigate treatment options, insurance coverage, and medication costs while avoiding counterfeit or inappropriate alternatives

Other conditions worth considering include: Type 2 diabetes or pre-diabetes , where insulin resistance affects how the body processes and stores energy Cushing's syndrome , caused by excess cortisol, which promotes central weight gain Perimenopause and menopause , which are associated with hormonal changes that can affect body composition and fat distribution Obstructive sleep apnoea (OSA) , which disrupts sleep quality and is associated with weight gain and metabolic changes Depression and anxiety , which can affect appetite regulation, sleep, and motivation Heart, kidney, or liver conditions , which can cause fluid retention and apparent weight gain Certain medicines , including corticosteroids, some antidepressants (such as mirtazapine), some antipsychotics, insulin, sulfonylureas, pioglitazone, valproate, and some gabapentinoids, which may promote weight gain as a side effect
Plan B does not terminate an existing pregnancy