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Moreover, most of the existing preclinical studies have relied on male rodents, neglecting sex-specific variants in gut microbiota compositions and neuroinflammatory responses (Lu et al., 2024)

Reverse transfection of imBA cells for siRNA-mediated knockdown (siLrp1 #s69313 and control #4390843, Ambion, Kassel Germany) was performed as previously described 26

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