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Risk of bias 10 of 11 studies were judged to be at low risk of bias across all RoB2 [10] domains, including randomisation and allocation (D1), deviations from intervention (D2), missing outcome data (D3), measurement of outcome (D4) and selection of reported results (D5)

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This decision affects millions of Medi-Cal enrollees in California

Tirzepatide is a synthetic peptide that mimics two incretin hormones, GLP-1 and GIP, which play critical roles in blood sugar regulation and appetite control

Its a complex challenge shaped by hormones, exhaustion, and time (or lack of it)