Based on the working hypothesis of P-gp-dependent collateral sensitivity [14,15,16,17], we examined the ability of tamoxifen as a collateral sensitivity drug for two reasons: a) tamoxifen has been previously shown to activate P-gp ATPase at clinically achievable concentration (46 M) [20, 21], and b) tamoxifen is widely used in the treatment of estrogen receptor-positive breast cancer [22]
Recalls & Warnings April 11, 2013 Chinese Herbal Manufacturer Warned For CGMP Violations On March 20, 2013, the FDA issued a warning letter to Finemost Corporation, dba Qualiherb, following a facility inspection which found the company's supplements, including Yi Zhi Tang and C
Analysis of MRAB Biofilm Architecture Using Confocal Laser Scanning Microscopy (CLSM) To initiate biofilm growth, 500 L MRAB-3 (OD 600 = 0.5 0.05) in TSB was added to microscope glass slides and incubated at 37C in a static incubator for 48 h
In general, people with diabetes can donate plasma, but certain factors related to diabetes may impact eligibility
paper proposed to use POLY-SVM, RBF-SVM and normalized POLY-SVM method in predicting the drug permeability of BBB which is based on clinical features 29
