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Similarly, a study based on swimming exercise for a total of four hours showed an increase in NAD + levels, yet also in this case, no measurements of mitochondrial function were performed 309 , reinforcing the need for more exercise-based investigations to further define how NAD + and mitochondrial homeostasis are perturbed and connected during exercise

doi: 52

If the intestinal lining is damaged by inflammation, infection, or bacterial overgrowth, those receptors do not function properly

So the lactate doesn't have to get in

This antioxidative potential arises from its ability to neutralize free radicals, particularly when regenerated by co-antioxidants like vitamin C and glutathione, which stabilize its effects and prevent the loss of its antioxidative capacity 177