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The human UT-A isoforms that are identified as UT-A1, UT-A3, and UT-A6 are encoded by the mRNAs transcribed from the UT-A promoter of the human SLC14A2 gene while the UT-A2 isoform is encoded by the mRNA transcribed from the human UT-A promoter

Exercise-induced ROS generation can alter this sequence (Figure 1)

Although they are inhibited by GPX4 inhibitors such as RSL3 in vitro , treatment of cells with more specific TrxR inhibitors, e.g., TRi, does not induce ferroptosis [102] indicating that TrxR is not directly involved in ferroptosis

Fan Z, Wirth AK, Chen D, Wruck CJ, Rauh M, Buchfelder M, et al

3.2.5 Immune responses (cytokines, receptors and innate immunity markers) Eight interleukin (IL) genes were expressed in ASG-10, the majority of which (IL-34, pro-IL-16-like, IL-12 subunit-like and IL-18) were detected at lower levels in the cells compared with gill (Log2fc between 4 and 1.6, Table 5)