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Amylin/leptin synergy is absent in extreme obesity and not restored by calorie restriction-induced weight loss in rats

The diet is very restrictive and doesnt allow for much variation or adjustments based on cravings or instinctual eating

Each individuals weight loss journey after bariatric surgery is different

Someone without that dysregulation, whose fullness signals are intact, doesn't have the same problem to solve

When injecting Ozempic in the stomach, choose a spot at least 2 inches away from your belly button and avoid your waistline to prevent clothing rubbing against the injection site and creating irritation