Retatrutide may suit individuals seeking significant, medically supervised weight loss who are interested in an emerging, next-generation peptide therapy
Insurance can significantly reduce the out-of-pocket cost if Wegovy is covered, but at the moment, many plans do not cover anti-obesity medications
Raftery T, Martineau AR, Greiller CL, Ghosh S, McNamara D, Bennett K, Meddings J, OSullivan M
Walensky LD, Kung AL, Escher I, Malia TJ, Barbuto S, Wright RD, Wagner G, Verdine GL, Korsmeyer SJ (2004) Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix
The recommended starting dose is 0.25 mg per week, which can be increased to 0.5 mg per week after four weeks if tolerated