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"This research shows that alpha cells are more flexible than we imagined," said Campbell, an associate professor in the Division of Endocrinology in the Department of Medicine and a member of the Duke Molecular Physiology Institute

Explaining metabolic adaptation helps normalize treatment plateaus and reduces discouragement

In addition to its benefits in diabetes and cancer, metformin has been shown to promote weight loss and protect against cardiovascular disease, Alzheimer disease, and non-alcoholic fatty liver disease (Forouzandeh 2014

Here is the straightforward answer: yes, metformin and tirzepatide can be taken together

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