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It was first characterized by Professor Predrag Sikiric and colleagues at the University of Zagreb in the early 1990s

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Notably, while KPV may be less potent than -MSH, it still exerts considerable anti-inflammatory effects, particularly in mitigating immediate inflammatory responses

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Herniated discs affect roughly 2% of the general population at any given time, with the L4-L5 and L5-S1 levels accounting for approximately 95% of lumbar herniations