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Further studies are warranted to assess the exact site of absorption and the optimal dosage for the desired action with tolerable adverse effects

Retatrutide: the triple agonist Retatrutide activates GLP-1, GIP, and glucagon receptors

Thyroid C-Cell Tumors: In mice and rats, semaglutide (the active ingredient in Wegovy and Ozempic) caused an increase in thyroid C-cell tumors, including medullary thyroid carcinoma (MTC)

Off-label use for low-BMI cosmetic weight loss is not supported by the evidence, exposes the patient to real risks (including rapid muscle loss and rebound after discontinuation), and typically isn't covered by insurance