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Rivfloza met the primary endpoint in PHYOXTM2 as patients in the treatment group saw a marked reduction from baseline in 24-hour-urinary oxalate (Uox) excretion from Day 90 to Day 180, according to Novos press release announcing the decision

Memory fails when you have multiple vials

Theyre not interchangeable, and neither is universally better

IBD patients have been reported to express variants of the IL-23 receptor potentially accounting for excessive inflammation and the immune-mediated removal of commensal species in the gut (Duerr et al

That success has been driven largely by GLP-1 therapies such as semaglutide and tirzepatide, developed by Novo Nordisk and Eli Lilly