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Thus, ASD is characterized by an imbalance of the processes of mitochondrial fusion, fission, and mitophagy that leads to contamination of the brain with dysfunctional mitochondrial fragments, insufficient energy supply to the brain tissues, and as a result, impairments of memory and synaptic function [187] contributing to ASD pathogenesis

During life, the BBB is subjected to perturbations and stresses from a wide range of endogenous or exogenous sources, which can promote brain health or can lead to brain pathologies

Both of these categories of supplements are very opportunistically taking advantage of the lax laws around supplements to jump in and try to profit from a group of medications that are truly effective, says Pieter Cohen, an associate professor of medicine at Harvard Medical School who studies supplements

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