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The appetite-suppressing and GI-motility-altering effects of GLP-1 receptor agonists can reduce salivary flow in some patients, potentially exacerbating Sjogren's oral symptoms

Anecdotal reports from the peptide community are more positive than the clinical data suggests, with some users claiming noticeable reductions in stubborn body fat, particularly in the abdominal area

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Most studies on humans are using dosages between 250 and 500 milligrams per day, so this is above that