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These results raised the possibility that the inhibition of OA-induced GLP-1 and PYY release by L-cysteine or H 2 S donors could be due to inhibition of targets downstream of G s /cAMP

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While researchers are always looking for synergy, its equallyif not morelikely that mixing them could lead to an antagonistic (blocking) or simply redundant effect due to receptor saturation

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References van Gorkom BA, Karrenbeld A, van Der Sluis T, Koudstaal J, de Vries EG, Kleibeuker JH (2000) Influence of a highly purified senna extract on colonic epithelium