Baseline bone density screening via DEXA scan is reasonable for individuals over 50, those with a family history of osteoporosis, or anyone with risk factors including prior fractures or prolonged corticosteroid use
The ATTAIN-MAINTAIN trial validated that patients can switch from tirzepatide to orforglipron and maintain their weight loss, establishing a potential sequential treatment paradigm: injectable first for maximum loss, t
Initial Combination Therapy with Metformin A total of 1091 patients with type 2 diabetes and inadequate glycemic control on diet and exercise participated in a 24-week, randomized, double-blind, placebo-controlled factorial study designed to assess the efficacy of sitagliptin as initial therapy in combination with metformin
What we do have is clinical experience, an understanding of how these medications work, and emerging concerns from the eating disorder treatment community
2038 How long is too long