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Gastrointestinal effects nausea, vomiting, diarrhea, and constipation are the most common and can be amplified when two appetite-suppressing compounds are used together

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While these can reduce inflammation, they often bring difficult side effects: Weight gain, bloating, and bone loss Increased infection risk Fatigue and mood changes High long-term costs Because these drugs suppress the immune system instead of balancing it, flare-ups frequently return once treatment stops