GLP-1 receptor agonists act downstream, targeting the visceral fat accumulation, insulin resistance, and dysregulated appetite that estrogen's absence creates
Allergen note: Stimulant-free
Vehicle-treated mice showed rapid weight loss, reflecting the catabolic state of uncontrolled diabetes
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We speculate that LC may improve myocardial metabolic remodeling by inhibiting PI3K/Akt signal transduction, which could be linked to increased expression of the mitochondrial key regulator PGC-1