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These results confirm the strong stability of the pooled effect size, and show that there was no study, which had a disproportionate effect on the overall results, in support of the strength of the association between GLP-1 RA use and risk of depression

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The mechanism makes physiological sense

A detailed exposition of methodological approaches required to conclusively establish the presence of the deficient/sufficient subtype can be found elsewhere ( The lack of significant mean difference, despite a trend toward GSH-deficit in schizophrenia, compared to the two prior meta-analyses ( We highlight several limitations of this meta-analysis of variance

GLP-1 drugs are not benign