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By hyperactivating the hypothalamic-pituitary-adrenal (HPA) axis, retinoic acid, the active form of vitamin A, has been related to depressed behavior

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An induced-colitis study in a murine model confirmed the decrease in butyrate-producing Clostridium clusters and reduced butyrate levels in the gut, which facilitated gut epithelial oxygenation and growth of Salmonella enterica serovar Typhimurium (S

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Although the decrease of Nrf2 down-regulated GPX4 expression Nrf2 did not impair STING mRNA and protein expression levels in murine cells (Gunderstofte et al., 2019)