One of the mechanisms supporting this resistance is the interaction between FOXO4 and p53 within the nucleus
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It may also be picking up a real limit: that the sense of feeling better, once weighed against nausea, muscle loss and the burden of a long-term injectable, is smaller and less durable than it looks in the clinic
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Large real-world UK CPRD cohort suggesting lower cardiovascular and serious kidney event rates with combination therapy
