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The rare red flag Very occasionally, persistent twitching that spreads, forces the eye closed, or involves other facial muscles can point to a condition called blepharospasm or a neurological cause

Mechanistically, the common thread appears to be dampening drug-evoked dopamine signaling in the nucleus accumbens and engaging GLP-1 anti-craving circuits involving the VTA, nucleus accumbens, lateral septum, laterodorsal tegmentum, and nucleus tractus solitarius

The company was acquired in October at a discount by private equity firm Madryn Asset Management

None of the participants experienced acute pancreatitis