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The one percent of calcium not stored in the skeletal system performs vital functions including transmission of nerve impulses, muscle contraction, activation of several coagulation factors involved in blood clotting, modulation of wound healing, communication between immune cells, insulin secretion from pancreatic beta-cells, and cellular signaling

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Nonetheless, our present findings are surprising since sex differences in disc health in humans are not commonly reported and because histopathology and MRI studies report contradictory evidence [16, 17]

Mas-Bargues et al., 2021)