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The liver is a major site of SAM production and methionine metabolism

J Phytopathol 152:529536 Kuniak E, Skodowska M (2005a) Fungal pathogen-induced changes in the antioxidant systems of leaf peroxisomes from infected tomato plants

Gateva P, Hristov M, Ivanova N, Vasileva D, Ivanova A, Sabit Z, Bogdanov T, Apostolova S, Tzoneva R (2024) Antinociceptive behavior, glutamine/glutamate, and neopterin in early-stage streptozotocin-induced diabetic neuropathy in liraglutide-treated mice under a standard or enriched environment

You can, but it is not recommended