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Ongoing trials Trials like NCT07328100 (intravenous coenzyme I for vascular aging, 2026 start) and NCT05243290 (oral NR in Gulf War Illness) continue to expand the human evidence base

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Researchers couldnt make the IGF-diabetes association in people over age 65 Better Heart Health In 15-years prospective study of 231 cases and 374 matched controls without any sign of ischemic heart disease (IHD) at the baseline of the study, those with baseline IGF-I levels in the lowest quartile had a 2-fold increased risk of IHD (when the major IGF-binding protein, IGFBP-3, was controlled)

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