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Consequently, adjuvant treatment was not administered to the patient who was advised regular follow-up and observation instead

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Off-Label Usage Weight loss in non-diabetics Obesity or metabolic syndrome Polycystic ovary syndrome (PCOS) Prediabetes in high-risk individuals Off-label use is common and should be guided by a healthcare professional with experience in metabolic disease

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To further investigate the localization of MC4R relative to -opioid receptors in the central nervous system (CNS), we analyzed publicly available transcriptomic data (brain atlas) from six postmortem human brains ( e/e 30 ) and identified multiple additional regions showing enrichment for both MC4R and OPRM1 (fig