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Gut-derived immune activation exacerbates central pathology in stroke and in autoimmune diseases like MS, while there is evidence that dietary interventions and probiotics can also attenuate disease severity and improve functional outcome

doi: 10.1007/s13258-022-01250-z

12 Another possibility may be uncertainties related to GLP-1 RA administration increasing heart rate and the latter having been associated with cardiovascular mortality

The lower doses are designed to minimize nausea and other side effects not to drive weight loss

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