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Among the most promising markers there are: urinary melatonin metabolites (such as 6-sulfatoxymelatonin or aMT6s), salivary or serum cortisol profiles, DNA methylation signatures in clock and tumor suppressor genes, telomere elongation patterns, and altered circulating microRNAs (miRNAs) levels 32,33

S.ShojaeianF.et al

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Based on the assumption that a ternary complex is formed between PfGrx, GSH, and roGFP2 WT (S 2 ), we estimated true k red values from tertiary plots at variable GSH concentrations of 7.3 10 5 M 2 s 1 and 1.3 10 5 M 2 s 1 for PfGrx C88S and PfGrx C32S/C88S , respectively (Fig

The monochlorobimane reagent was prepared by reconstitution in DMSO per manufacturers directions