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This is because Vitamin B12 is involved in synthesizing serotonin, a neurotransmitter responsible for regulating mood

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"They just want to post [on social media] about how much weight they lost and, 'Go on it!'" Reilly's doctor suggested reducing her dose back down 5 milligrams in the hopes that her side effects would be milder

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Journal of Pharmaceutical Sciences 99 , 22002208, doi:10.1002/jps.21989 (2010)

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