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Twenty-five rats were randomly divided into five groups: the control group, model group, and three BPC 157-treated groups (10 g/kg, 20 g/kg, and 40 g/kg)

104 (Suppl 4), 715740 (1996)

FDA approval is not expected before late 2027

5 Conclusions While icodec pharmacokinetics and semaglutide total exposure were unaffected by the combination of icodec and semaglutide in IcoSema, the maximum concentration of semaglutide was higher and occurred earlier presumably owing to icodec outcompeting semaglutide for albumin binding locally at the injection site

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