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It may reduce redness and irritation of the skin

The effect of excess I on thyroid follicular cells (TFCs) obtained from HT patients resulted in inhibition of autophagy, autophagy-associated protein LC3B-II (lain chain 3B-II), TGF-1, and increased ROS production, caspase-3 activation and apoptosis of TFC, the Akt/mTOR signaling pathway (46)

While this protective mechanism is beneficial, excessive melanin production can lead to issues such as hyperpigmentation, dark spots, and uneven skin tone

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In RCC, PROTAC PpD promotes the ubiquitinated degradation of P21-activated kinase-4 (PAK4), which in turn inhibits tumor proliferation and increases tumor cell death by immune cells[85]